Glycated LDL is a form of low-density lipoprotein in a sugar molecule attached. This component of blood is known as “bad cholesterol” and the latest research shows that if a person has diabetes or not, are at increased risk of a heart attack.
It is a fact that Glycated LDL is higher in diabetics than nondiabetics. However, a recent study has shown that Glycated increase the risk of heart attacks in people with diabetes and those without diabetes.
online edition of “Nutrition, Metabolism and Cardiovascular Disease” published the results of this study in December 2006, it has shown that people with the highest LDL levels had twice the risk of having a heart attack and it is for diabetics and those who are not.
Diabetes is a risk factor for heart attack and myocardial infarction might be associated with Glycated LDL, it is more readily oxidized than normal LDL and more easily metabolized by the macrophages.
That's because the sugar molecule attached to the apoprotein B-A apoprotein is a protein characteristic prostheses without his group LDL interferes with the link to the apoprotein with his membram receiver.
Macrophages is a great immune cell that devours invading pathogens and other intruders. It stimulates other immune cells by offering them small pieces of the invader. Macrophages may harbor large quantities of HIV without being killed, acting as reservoirs of the virus and, last but not least, macrophages are precursors of cells in the foam of the atherosclerotic plaque.
Glycated apoprotein B is also present in nondiabetic and its increase may be due to the temporary hyperglycemia caused by a high glycemic load of meals, by stress and by d ' ; other conditions.
All the study participants took blood samples, as
-Levels of fasting glucose
Insulin-
-Cholesterol-
Triglycerides
-HDL, the good cholesterol
-and LDL
– Glycated LDL
People who have had a heart attack and those who had not been measured, the only thing that was higher in both diabetic and nondiabetic case was Glycated LDL.
However, these results must be confirmed and if the relationship is confirmed, interventions aimed at reducing glycation lipoprotein-a combination of fats and proteins that carry lipids (fats) in the blood should be held to determine whether such an intervention may reduce the risk of coronary heart disease.
In 4452 participants, who had not had a heart attack when the study began, 103 people developed a heart attack in five years, 34 of them have diabetes at the beginning and 69 were not.
Heart Attack And Glycated LDL
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